Endocrine Abstracts

Introduction: Deficiency of 11-beta hydroxylase (11-HD) accounts for 5% of the causes of congenital adrenal hyperplasia (CAH), with an incidence of 1:100,000. The classic form phenotype consists in an excess of androgens and mineralocorticoids, which clinically translates into hypertension and hypokalaemia. In boys, there may be an increase in penis size, early adrenarche, increased growth velocity, and advancing bone age.Clinical case: We present a case...

Introduction: Diabetes mellitus (DM) is a chronic disease with increasing incidence worldwide, mostly in younger ages. Diabetic kidney disease (DKD) is a main complication, with a prevalence of 20-40%, associated with high cardiovascular mortality. Despite the association of type 2 diabetes (T2D) in young adults with rapid progression to DKD, in type 1 diabetes (T1D) this is not well established. Other complications have also a high impact on life quality.<p class="abstext...

Introduction: Multiple pituitary adenomas (PA) have a prevalence of 0.2-2.6% of all resected PAs. However, most of them are simultaneously diagnosed and in the setting of acromegaly. In a 2019 surgical series with 22 cases of multiple PAs, only one case was asynchronous and all of them had a positive immunohistochemical staining.Case report: A 32-year-old woman (1996) was referred to na Endocrinology appointment with amenorrhea and weight gain for the la...

Aim: Dose corrected for thyroid gland size is one of the methods used to determine radioactive iodine (RAI) activity for patients with Graves disease (GD). This study was aimed to investigate the real-world success rate of this method and the predictors of success after first treatment.Methods: This is a retrospective study of 80 patients with GD treated between 2014 and 2020 in a tertiary referral hospital in Almada, Portugal. The successful group was d...

Introduction: In the last years, we have seen a high migration rate of people to Portugal. Not much is known about diet and lifestyle habits in some of these migrant women with gestational diabetes mellitus (GDM). On the other hand, communication can be a barrier and health care access may be more limited. For this reason, it is important to investigate whether there are differences in outcomes between these two populations, in order to question the need to change our clinical...